To facilitate transplantation, the US is divided into 11 geographic regions. In each region, a regional councilor, an associate regional councilor, and a staff administrator work together to coordinate regional activities and present informational forums for transplant professionals and patients. Each region is represented on the Board of Directors and on each of the standing committees.

These regions also play a role in organ allocation. With the exception of perfectly matched donor kidneys, organs are offered to sick patients within the area in which they were donated before being offered to other parts of the country. This helps to:

• reduce organ preservation time;
• improve organ quality and survival outcomes;
• reduce the costs incurred by the transplant patient; and
• increase access to transplantation.

The states comprising each region are as follows:

• Region 1: Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island, Eastern Vermont
• Region 2: Delaware, District of Columbia, Maryland, New Jersey, Pennsylvania, West Virginia, Northern Virginia
• Region 3: Alabama, Arkansas, Florida, Georgia, Louisiana, Mississippi, Puerto Rico
• Region 4: Oklahoma, Texas
• Region 5: Arizona, California, Nevada, New Mexico, Utah
• Region 6: Alaska, Hawaii, Idaho, Montana, Oregon, Washington
• Region 7: Illinois, Minnesota, North Dakota, South Dakota, Wisconsin
• Region 8: Colorado, Iowa, Kansas, Missouri, Nebraska, Wyoming
• Region 9: New York, Western Vermont
• Region 10: Indiana, Michigan, Ohio
• Region 11: Kentucky, North Carolina, South Carolina, Tennessee, Virginia